- Three Stories
- 937 Liberty Avenue, Pittsburgh, PA, 15222
- Thunderbird Cafe & Music Hall
- 4053 Butler Street, Pittsburgh, PA, 15201
- Tomayko Foundation & Gallery
- 5173 Liberty Avenue, Pittsburgh, PA, 15224
- ToonSeum
- 945 Liberty Avenue, Pittsburgh, PA, 15222
- Tower At PNC Plaza
- 300 Fifth Avenue, Pittsburgh, PA, 15222
- Trace Brewing
- 4312 Main Street, Pittsburgh, PA, 15224
- Trinity Cathedral
- 325 Sixth Avenue, Pittsburgh, PA, 15222
- True T Studios
- 4623 Liberty Avenue, Pittsburgh, PA, 15224
- Trust Arts Education Center
- 805 Liberty Avenue, Pittsburgh, PA, 15222
- Trust Oasis
- 133 Seventh Street, Pittsburgh, PA, 15222