- Settlers Ridge
- 200 Settlers Ridge Center Drive, Pittsburgh, PA, 15205
- Seven Springs Mountain Resort
- 777 Waterwheel Drive, Seven Springs, PA, 15622
- Shadyside Presbyterian Church
- 5121 Westminister Place, Pittsburgh, PA, 15232
- Shenot Farm & Market
- 3754 Wexford Run Road , Wexford, PA, 15090
- Sheraton At Station Square
- 230 West Station Square Drive, Pittsburgh, PA, 15219
- SideQuest On 44th (Formerly Cattivo)
- 146 44th Street, Pittsburgh, PA, 15201
- Sienna Mercato
- 942 Penn Avenue, Pittsburgh, PA, 15222
- Silver Eye Center For Photography
- 4828 Penn Avenue, Pittsburgh, PA, 15224
- Simple Greek, The (Market Square)
- 431 Market Street, Pittsburgh, PA
- Sixth & Penn Garage
- 546 Penn Avenue, Pittsburgh, PA, 15222